44 research outputs found
Artists' books at the Centre for Fine Print Research
An article on artists' books at the Centre for Fine Print Research
A Manifesto for the Book
What will be the canon for the artistâs book in the 21st Century? In an arena that now includes both digital and traditionally produced artistsâ books, what will constitute the concepts of artistsâ publishing in the future?This project was funded by the Arts and Humanities Research Council from March 2008 - February 2010. This project investigated and discussed issues concerning the context and future of the artistâs book, in an attempt to extend and sustain critical debate of what constitutes an artistâs book in the 21st Century.One of the key points of this project was to try and include all the book related activity that artists engage with. To include work that was being produced on, and exclusively for, digital technologies within the book arts field, and not leave it floundering uncomfortably on the edge, or subjected to a different terminology altogether, if the artist considered what they were producing to be a book, then we felt it should be included. We also looked at the continued practice of traditional production processes for artistsâ books such as letterpress, etching, lithography, screenprint and woodcut, and have interviewed a range of artists and publishers who work with these, as well as those producing livres dâartistes, fine press books, design bindings, multiples, installation and audio books.Bodman will give a conference paper on this book at the IMPACT 7 International Multi-Disciplinary Printmaking Conference at University of Melbourne 27-30 September 2011. Topic 14: Printmedia and the Artists' Book - paper title âA Manifesto for the Book - artist's book - artist's publication - book art?â. http://impact7.org.au/program_wednesday.htm
Un Manifesto para o Livro (A Manifesto for the Book)
A Manifesto for the Book was first published as a free online download as part of the findings from a two-year AHRC funded research project on the future of the artistâs book in the digital age(http://www.bookarts.uwe.ac.uk/canon.htm). The manifesto, co-authored by Bodman and Sowden was republished by invitation of the Editor in Chief JosĂ© BĂĄrtolo, ESAD, Portugal, in PLI magazine, in English and Portuguese. PLI is a Portuguese, quarterly magazine devoted to design criticism and practice published by ESAD/Escola Superior de Artes e Design de Matosinhos (the Matosinhos Institute of Art and Design), (www.esad.pt). This particular double issue âEntusiasmoâ is about publishing: self-publishing, DIY, big books, artistsâ books, publishing as cultural and political production.Dedicated to the theme of Enthusiasm, in this issue of PLI, the desire to affirm the strength of art & design at a time of economic crisis is strongly visible. It is a double issue (no. 2/3) which features a wide range of national and international contributors, a total of 36 authors working in the areas of design, architecture, photography and contemporary thought. With more than 200 content-filled pages, this issue of PLI stands out in that its physical structure has turned it into a real piece of design, encompassing 5 different formats, various different types of paper and exploring differing graphic solutions that culminate in a magazine with a very strong visual presence.Contributors: AntĂłnio Quadros Ferreira, AntĂłnio Silveira Gomes, AntĂłnio Olaio, Atelier do Corvo, Brad Freeman, Caroline NiĂ©mant, Derek Birdsall, Emanuel Barbosa, Francisco Laranjo, Henrique MagalhĂŁes, Isabel Baraona, Isabel Lucena, Ken Garland, Kiluanji Kia Henda, JosĂ© Albergaria, JosĂ© BĂĄrtolo, JosĂ© BrandĂŁo, LuĂs Miguel Castro, Margarida Azevedo, Maria JoĂŁo Baltazar, MĂĄrio Moura, Patrick Lasey, Paolo Deganello, Paulo T. Silva, Richard Kostelanetz, Roberto Vidal, Roger Sabin, Roger Willems, Sarah Brasseur, Sarah Bodman, Silvia PrudĂȘncio, Steven McCarthy, Susana Carvalho, Susanna Edwards, Tom Sowden, Tony White, Vera Tavares
Identifying inequitable healthcare in older people: systematic review of current research practice
There is growing consensus on the importance of identifying age-related inequities in the receipt of public health and healthcare interventions, but concerns regarding conceptual and methodological rigour in this area of research. Establishing age inequity in receipt requires evidence of a difference that is not an artefact of poor measurement of need or receipt; is not warranted on the grounds of patient preference or clinical safety; and is judged to be unfair.
A systematic, thematic literature review was undertaken with the objective of characterising recent research approaches. Studies were eligible if the population was in a country within the Organisation for Economic Co-operation and Development and analyses included an explicit focus on age-related patterns of healthcare receipt including those 60 years or older. A structured extraction template was applied. Extracted material was synthesised in thematic memos. A set of categorical codes were then defined and applied to produce summary counts across key dimensions. This process was iterative to allow reconciliation of discrepancies and ensure reliability.
Forty nine studies met the eligibility criteria. A wide variety of concepts, terms and methodologies were used across these studies. Thirty five studies employed multivariable techniques to produce adjusted receipt-need ratios, though few clearly articulated their rationale, indicating the need for great conceptual clarity. Eighteen studies made reference to patient preference as a relevant consideration, but just one incorporated any kind of adjustment for this factor. Twenty five studies discussed effectiveness among older adults, with fourteen raising the possibility of differential effectiveness, and one differential cost-effectiveness, by age. Just three studies made explicit reference to the ethical nature of healthcare resource allocation by age. While many authors presented suitably cautious conclusions, some appeared to over-stretch their findings concluding that observed differences were âinequitableâ. Limitations include possible biases in the retrieved material due to inconsistent database indexing and a focus on OECD country populations and studies with English titles.
Caution is needed among clinicians and other evidence-users in accepting claims of healthcare âageismâ in some published papers. Principles for improved research practice are proposed.This research was funded by the National Institute for Health Researchâs School for Public Health Research
Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration
The loss of cone photoreceptors that mediate daylight vision represents a leading cause of blindness, for which cell replacement by transplantation offers a promising treatment strategy. Here, we characterize cone differentiation in retinas derived from mouse embryonic stem cells (mESCs). Similar to in vivo development, a temporal pattern of progenitor marker expression is followed by the differentiation of early thyroid hormone receptor ÎČ2-positive precursors and, subsequently, photoreceptors exhibiting cone-specific phototransduction-related proteins. We establish that stage-specific inhibition of the Notch pathway increases cone cell differentiation, while retinoic acid signaling regulates cone maturation, comparable with their actions in vivo. MESC-derived cones can be isolated in large numbers and transplanted into adult mouse eyes, showing capacity to survive and mature in the subretinal space of Aipl1â/â mice, a model of end-stage retinal degeneration. Together, this work identifies a robust, renewable cell source for cone replacement by purified cell suspension transplantation
Rationale, design and methods of the Study of Work and Pain (SWAP): a cluster randomised controlled trial testing the addition of a vocational advice service to best current primary care for patients with musculoskeletal pain (ISRCTN 52269669)
Background
Musculoskeletal pain is a major contributor to short and long term work absence. Patients
seek care from their general practitioner (GP) and yet GPs often feel ill-equipped to deal with
work issues. Providing a vocational case management service in primary care, to support
patients with musculoskeletal problems to remain at or return to work, is one potential
solution but requires robust evaluation to test clinical and cost-effectiveness.
Methods/Design
This protocol describes a cluster randomised controlled trial, with linked qualitative
interviews, to investigate the effect of introducing a vocational advice service into general
practice, to provide a structured approach to managing work related issues in primary care
patients with musculoskeletal pain who are absent from work or struggling to remain in work.
General practices (n = 6) will be randomised to offer best current care or best current care
plus a vocational advice service. Adults of working age who are absent from or struggling to
remain in work due to a musculoskeletal pain problem will be invited to participate and 330
participants will be recruited. Data collection will be through patient completed
questionnaires at baseline, 4 and 12 months. The primary outcome is self-reported work
absence at 4 months. Incremental cost-utility analysis will be undertaken to calculate the cost
per additional QALY gained and incremental net benefits. A linked interview study will
explore the experiences of the vocational advice service from the perspectives of GPs, nurse
practitioners (NPs), patients and vocational advisors.
Discussion
This paper presents the rationale, design, and methods of the Study of Work And Pain
(SWAP) trial. The results of this trial will provide evidence to inform primary care practice
and guide the development of services to provide support for musculoskeletal pain patients
with work-related issues.
Trial registration
Current Controlled Trials ISRCTN52269669
Pain Control in Breast Surgery: Survey of Current Practice and Recommendations for Optimizing ManagementâAmerican Society of Breast Surgeons Opioid/Pain Control Workgroup
Introduction: The opioid epidemic in the United States is a public health crisis. Breast surgeons are obligated to provide good pain control for their patients after surgery but also must minimize administration of narcotics to prevent a surgical episode of care from becoming a patient's gateway into opioid dependence.
Methods: A survey to ascertain pain management practice patterns after breast surgery was performed. A review of currently available literature that was specific to breast surgery was performed to create recommendations regarding pain management strategies.
Results: A total of 609 surgeons completed the survey and demonstrated significant variations in pain management practices, specifically within regards to utilization of regional anesthesia (e.g., nerve blocks), and quantity of prescribed narcotics. There is excellent data to guide the use of local and regional anesthesia. There are, however, fewer studies to guide narcotic recommendations; thus, these recommendations were guided by prevailing practice patterns.
Conclusions: Pain management practices after breast surgery have significant variation and represent an opportunity to improve patient safety and quality of care. Multimodality approaches in conjunction with standardized quantities of narcotics are recommended
Data from a pre-publication independent replication initiative examining ten moral judgement effects
We present the data from a crowdsourced project seeking to replicate findings in independent laboratories before (rather than after) they are published. In this Pre-Publication Independent Replication (PPIR) initiative, 25 research groups attempted to replicate 10 moral judgment effects from a single laboratory's research pipeline of unpublished findings. The 10 effects were investigated using online/lab surveys containing psychological manipulations (vignettes) followed by questionnaires. Results revealed a mix of reliable, unreliable, and culturally moderated findings. Unlike any previous replication project, this dataset includes the data from not only the replications but also from the original studies, creating a unique corpus that researchers can use to better understand reproducibility and irreproducibility in science
The pipeline project: Pre-publication independent replications of a single laboratory's research pipeline
This crowdsourced project introduces a collaborative approach to improving the reproducibility of scientific research, in which findings are replicated in qualified independent laboratories before (rather than after) they are published. Our goal is to establish a non-adversarial replication process with highly informative final results. To illustrate the Pre-Publication Independent Replication (PPIR) approach, 25 research groups conducted replications of all ten moral judgment effects which the last author and his collaborators had âin the pipelineâ as of August 2014. Six findings replicated according to all replication criteria, one finding replicated but with a significantly smaller effect size than the original, one finding replicated consistently in the original culture but not outside of it, and two findings failed to find support. In total, 40% of the original findings failed at least one major replication criterion. Potential ways to implement and incentivize pre-publication independent replication on a large scale are discussed
A many-analysts approach to the relation between religiosity and well-being
The relation between religiosity and well-being is one of the most researched topics in the psychology of religion, yet the directionality and robustness of the effect remains debated. Here, we adopted a many-analysts approach to assess the robustness of this relation based on a new cross-cultural dataset (N=10,535 participants from 24 countries). We recruited 120 analysis teams to investigate (1) whether religious people self-report higher well-being, and (2) whether the relation between religiosity and self-reported well-being depends on perceived cultural norms of religion (i.e., whether it is considered normal and desirable to be religious in a given country). In a two-stage procedure, the teams first created an analysis plan and then executed their planned analysis on the data. For the first research question, all but 3 teams reported positive effect sizes with credible/confidence intervals excluding zero (median reported ÎČ=0.120). For the second research question, this was the case for 65% of the teams (median reported ÎČ=0.039). While most teams applied (multilevel) linear regression models, there was considerable variability in the choice of items used to construct the independent variables, the dependent variable, and the included covariates